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Dr. Douglass's Practical HISTORY OF A New Epidemical Eruptive Milary Fever, with an Angina Ulcusculosa, &c.

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THE Practical HISTORY OF A New Epidemical Eruptive Mili­ary Fever, with an Angina Ulcusculosa Which Prevailed in Boston New-England in the Years 1735 and 1736.

By William Douglass, M. D.

BOSTON, N. E. Printed and sold by Thomas Fleet, at the Sign of the Heart and Crown in Cornhill. 1736.

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TO A Medical Society in Boston.

Gentlemen,

THIS Piece of Medical History does natu­rally address it self to you, considering that I have the pleasure of being one of your number, that you have been fellow labourers in the management of this distemper, and therefore competent judges of this performance, and that where difficult or extraordinary Cases have oc­curred in any of your private practice, I was favoured to visit the Patients in order to make a minute clinical enquiry: in short, without your assistance this piece would have been less perfect, and not so well vouched.

As this distemper continues to spread and pre­vail in several Towns of this and the neighbour­ing Provinces, I thought it might prove a piece of humanity and benevolence, if after many months diligent observations made in most of the varieties which occur in this Illness, I did en­deavour to reduce them to some easy distinct Historical and Practical Method. The vanity of appearing as an Author or writer was no in­ducement, because we all know that in a planta­tion life neither honour nor credit are to be acquired by writing. It is not published by way [Page ii]of a Quack bill to procure Patients and their money, as has been the practice of some void of modesty and truth; because the Distemper is al­most over in Boston, and while it prevailed here I could not well have attended more pati­ents than what I had from time to time under my care, and make with attention the proper observations at the same time.

A secondary reason for my writing is, to induce some Gentlemen of the profession in our other Provinces and Colonies, where this distemper does or may prevail; to give some account of its appearance with them, in order to discover what influence, progress of time, varieties of climate and Soil may have in the phoenomina of this disease. This method, of taking things originally that is from the life, if pursued (but by abler hands) in the Epidemical Distempers which may from time to time happen amongst us, may be of considerable advantage in Physick.

A Speculation that is a novelle might have been composed sooner, but not a real History: for as amongst Naturalists, many repeated obser­vations and experiments are requisite to form established truths or conclusions; so it ought cer­tainly to be in the practice of Medicine, where no affair of Speculation or curiosity, but the life and death of a fellow Citizen is the object of our enquiry.

Yours, &c. William Douglass.
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The Practical History of a new Epidemical Miliary Fever with an Angina Ʋlcusculosa.

THIS Distemper did emerge 20th. May, 1735. in Kingston Township 50 Miles Eastward from Boston; it was no foreign importation, Kingston being an inland place, of no Trade or considerable communication. The first seized was a child who died in three Days Illness; about a Week thereafter in another Family at four Miles distance, three Children were seized succes­sively, and died also the third Day; it continues spreading gradually in that Township, seizing here and there particular Families with that degree of violence, that of the first circiter forty decumbents none recovered as we were informed. It was vulgarly called the Throat Illness, or a Plague in the Throat, and alarmed the Provinces of New-England very much. Some died of a sudden or acute Necrosis; but most of them by a Symptomatick affiction of the Fauces or Neck; that is by Sphacelations or corrosive Ʋlcerations in the Fauces, or by an infiltration and tumefaction in the Chops and fore part of the Neck, so turged, as to bring all upon a level between the chin and sternum, occasioning a strangulation of the Patient in a very short time.

After a few Weeks it spreads into the neigh­bouring Townships, but with more mildness. The [Page 2]first appearance that we can recollect of it in Boston, was 20th August on a Child of Capt. Stannys at the North End; having white specks in the Throat, and a cutaneous efflorescence: A few more in the same Neighbourhood were seized in like manner, about the same time. Towards the end of Septem­ber it appeared in several parts of the Town, with a complaint of soreness in the Throat, Tonsils, swelled and speckt, Uvula relaxed, slight Fever, flush in the Face, and an Erysipelas like efflorescence on the neck, chest and extremities; but being of no fatal or bad consequence, nothing more than a common cold was suspected. Our first alarm was from a young Man How Aet. 20. in the beginning of October: His History runs thus; He was lately arrived from Exeter to the Eastward, where his Brother died of this Illness; his Symptoms were great prostration of Strength, a speck in one of the Tonsils, colliquative Sweats, Pulse not high and full, but low, hard, stringy, unequal and more frequent than natural, deglutition good to the last, no Sphacelation in the Throat, no eruption; from a rash inconsiderate opinion of forcibly quelling the Malignity, he was thrice let Blood, had some Emeticks and Cathar­ticks adminstred, and by profuse evacuations was gra­dually reduced, so as to die of a gentle decay of natural Strength, the 6th Day of Illness.

Beginning of November it spread considerably in Boston, especially amongst Children, with more vio­lent Symptoms, and severals die of it in various Periods: it seemed to be at the hight, as to Num­bers ailing and quantity of Deaths, the second Week of March; that Week there were 24 Buri­als, whereas communibus annis in that Season they are only 9 or 10 per Week.

[Page 3] It is generally in so considerable a Degree more favourable in Boston, than in the Townships where it first prevailed; that many can scarce be persuad­ed of its being the same Distemper: It is neverthe­less essentially the same, there is no Symptom, even the most malignant that has appeared in New-Hampshire, but what the like has occured in Boston. Perhaps Boston dry healthy air, good feeding, con­stitutions less Psorick, and the better management of the Sick, favoured us; the reasons for its proving more mortal in the other Towns, may be, the Country woodland and fresh water damps, (the Sheep in fenny lands are most susceptible of and suffer most by the Rot) their coarse Food, salt Pork diet, Psorick Constitutions, (which is one of the principal Endemial distemperatures in New-Eng­land) bad Lodgings, and that mischievous Practice of using this Distemper with profuse evacuations, whereby the laudable and salutary cuticular erupti­on has been so perverted as to be noticeable only in a few, and in these it was called a Scarlet Fever; the great prostration of Strength essential to this Distemper is so much increased, as to render Na­ture an under match for the assaults of this Illness and its consequences. In fact to the Eastward in some Country Towns, at certain times have died 1 in 3 of the Sick, in others 1 in 4, in scarce any fewer than 1 in 6, whereas in Boston not above 1 in 35 have died.

As in most Epidemical acute Illnesses, especially eruptive Fevers, (witness the Small Pox) so in this, are very many varities or degrees, from the most gentle and benign to the most malignant. Symptoms did vary chiefly from something inscrutable in the Constitutions of Families and Persons; the Scropho­lous and Psorick were the most susceptible of it, and [Page 4]did suffer most by it; the Regimen had a conside­rable influence, here some who might have surviv­ed the natural Symptoms did succumb by profuse U. S. and other evacuations, one of the most essen­tial Symptoms of this Distemper (as before hinted) being great prostration of Strength. In so great va­riety it is not possible to give any concise scholastick description, which may comprehend all: We shall therefore, as a Standard first describe the most fre­quent sort, as it appeared in good constitutions.

A previous listlesness and languishing counte­nance for a Day or two, or some other praenuncia as u. g. wet Nurses loosing their Milk. The first at­tack is somewhat of a chill or shivering; soon after follows Head ake or some other versatile spasmodick pains, as pain in the back, joints, side, a vomit­ing or nausea, or in some constitutions which are not easily provoked to vomit, only a certain unea­siness or sickness at Stomach; at the same time the Vvula but chiefly the Tonsils were tumified, inflam­eded and painful, with some white specks; then follows a flush in the Face and some miliary erupti­ons there, with a benign mild Fever, the same esflorescence soon after appears on the neck, chest and extremities; the 3d or 4th Day, Eruption is at the hight and well defined with fair intervals; the flushing goes off gradually, with a general itching; and in a Day or two more the cuticle scales or peels off, especially in the extremities: At the same time the cream coloured sloughs or specks in the Fauces become loose and cast off, and tumefactions there do subside. The Tongue from the beginning is fur'd as in a Mercurial ptyalism, urine high coloured, Blood by U. S. more florid than natural, in the whole course of the Distemper a very great prostra­tion [Page 5]of Strength, and faintness upon recovery, nervos pains and weakness in the joints, particularly in the neck, wrists and ancles; universal tenderness to the touch; a tickling guttural cough, some short Hec­tick flushings, and loss of enbon point. As in the Measles there is a peculiar smell, so in our Distem­per the effluvia from the Patient have a proper smell; in Children as if troubled with Worms, in grown Persons the rancid smell of foul Bed Linnen. The alvine excrement is of a dark cast and very fetid.

This Standard kind when left to nature, with a warm soft Regimen, had generally an easy and sa­lutary course in six or seven Days; but when by a hot cordial method, or on the other extreme, by being too much exposed to the cold, or by officious profuse evacuations Nature was difturbed in her Work; the Distemper was protracted, or some con­sequential ails from an imperfect defecation en­n|sued.

Where Nature required any assistance, the prin­cipal intentions were with regard to the cuticular eruption and the ulcuscula in the Throat. Any Af­fection of the Throat does frequently produce a natural ptyalism: Mercurials used with discretion are a kind of specifick in such like ulcers & ulcuscula, and in fact here they moistned the Throat and Mouth, stopt the spreading of the ulcuscula, and promoted the casting off of the sloughs; and as an accessory advantage (the Patients being mostly Children) destroy'd Worms: amongst all its pre­parations Calomel answered best, the gentle vomit­ing or few stools that it occasioned in some, did not confound the natural course of the Distemper: Turbith proves generally too strong a revulsion, and the Eruption is thereby too much diverted; this [Page 6]Distemper did not well bear any other evacuations but Mercurials. Any detergent Gargle, with an addition of the Tincture of Myrrh and Aloes, was of good use, especially for the Vlcuscula, and did promote the discharge of a ropy Phlegm lodged in the Fauces. As to the cuticular efflorescence, it was not a scarlet suffusion, but a miliary palpable erupti­on, or in lieu thereof in some constitutions a con­tinued gentle breathing Sweat; and in a very few, who have naturally a liberior transit us by the Pores than is usual, no sensible cuticular excretion; in all the morbid effluvia discovered themselves by their peculiar smell: These were with good effect solli­cited by Snake-root Tea; or (as in some Persons) where this did occasion an ardor or burning heat, instead of a breathing mellow Sweat, Sp. C. C. or any other volatile Spirit in small Herb Teas an­swered well. Blisters and Suppedanea, in the begin­ning where Symptoms were not violent, occasioned a protracted Eruption; in some immediately upon their application, the Eruptions vanished or became less vivid. When the Eruption began to decline a few loose Stools were very refreshing. The Pati­ent being up, and having recovered a competent degree of Strength, is to be purged once or twice, to carry off any feculency that may have remained in the Blood and Juices.

For a more distinct conception of the varities in this Distemper, they may be reduced to three Classes.

I. Those who die the first, second and third day of Illness, by an irremediable Necrosis of the Oeco­nomy: in such the Seizure is generally sudden, a sinking pain at the Stomach, an extreme prostra­tion of Strength, a titubating low pulse, in some a stupor, in others a delirium, in some children [Page 7]convulsions, and all of them generally die dozie: they are attended with some colliquation, as conti­nued vomiting, purging, profuse Sweats, bloated­ness of the habit, an infiltration like that of the Mumps vulgarly so called, one or more of these: in general the texture of their blood and juices is much destroy'd and rendred an incoherent puddle of corruption; in fact immediately upon (some­times before) their exit, they have an intolerable faetor. In this Class U. S. and other evacuations did accelerate death.

II. Those where the distemper has its common or ordinary course; here the 6 or 7 day seems to be critical, and the Symptoms of death or recovery do generally then begin to manifest themselves. Some by peculiarity of constitution, and from im­proper administrations do die or have an incipicent recovery sooner: others for the like reasons or some particular accidents (u. g. if about the time of regular monstruation, the complicated fret occasi­ons worse Symtoms, and of longer continuance) have this period protracted and in such (where death is inevitable) the Symptoms of death may continue a day or two longer, that is the Patient may die the eighth or ninth day. All who conti­nue Ill after that period, belong to the third Class, that is of consequential ails.

The Symtoms of bad Omen in this Class, are very great prostration of strength, dejection and despon­dency of mind, titubating low pulse, incessant vomitings purgings or sweats, Tonsils much in­flamed endangering strangulation, the specks in the Fauces of a brownish or leaden colour, or ragged and jagged, a continued jactantia in some, in others a stupor, refusal of assumenda even of diluting com­mon [Page 8]drinks, a dry parched skin, Eruptions appear­ing and disappearing alternately, Eruption univer­sal of a dark redish cast continuing crude many days (because in this as in all eruptive Fevers, the darker or more livid the efflorescence, the more malignant) where the miliary pustles are large, distinct and pale like a chrystaline Small-Pox; where strong Cordials and Alexipharmicks have been used, the face, eye-lids, arms, hands, legs, feet swell, and are of a dark red complexion, as in the most malignant Small-Pox; in children if the velum Palati be much affected, with an ichorous discharge by the Nose; where many mucous linings are expectorated, re­sembling the cuticle raised by Vesications; when pus was brought up, where no sloughs or exulcerati­ons could be seen in the Pauces; where without any difficulty in swallowing, this affection has reached down the Bronchia unto the Lungs with the Symptoms of a New-England Quinsey, and was erroniously deemed such: the deeper in the Thorax the complaint the greater the danger: in some young children with scarce any appearance in the Throat, spreading Ulcers did form behind the Ears in the place where Infants have a natural Issue or running. In some the Tongue did throw off a slough or Exuvia, retaining the impressions of the Papillae; being a Mucus inspissated, and of the same nature with those mucous linings expectora­ted from the Bronchia or Oesophagus. Some have had impostumations in the Fauces, with a fatal strangulation, while others have escaped by the discharge of Ichorous curdly matter. Some especi­ally of the adult female kind, have had Hysterical or Nervous Suffocations; but of no bad conse­quence, unless officiously and ignorantly treated with U. S. and other evacuations.

[Page 9] The Fever is seldom too high, sometimes it is too low for a thorough laudable Eruption. If the Fever is too high, if the patient is plethorick or accustomed to U. S.; take away some Blood but with discretion; if the Tonsils are much inflamed with great pain and difficulty in swallowing, use U. S. in the Jugulars, Epispafticks ad Nucham, en­courage the Eruption, or its succedaneum a breath­ing sweat; a profuse sudor is equally to be avoided as a continued Diarrhaea, either of them confound the distemper in its natural course. In case of colliquations give ol. Cinamomi, decoct. Alb. Elixir Vitriol, torrified Rhubarb and the like. As to the specks or sloughs in the Fauces (they cast of in course in the benign kind) Mercurials inwardly, and the Gargles before mentioned topically, are useful; the practice in some Country places of separating them forcibly by spatulas is hurtful, because the irritation occasioned thereby induces a further flux upon the part, and the sloughs form again worse conditioned than before. Where the Brain is af­fected as in Vigiliae, jactantia, delirium, Coma, stupor, glysters, Vesicatories & suppedanea are to be used. Where faintness or great prostration of strength, give toasted Bread soaked in some gene­rous Wine and Water, or volatile Spirits in their common drinks; Bezoars, Testacea and the like are of no use, the Shop Cordial Juleps and mixtures are only sugar'd drams. To enumerate all the other accidental Symptoms which do happen here, in common with other acute diseases, would be trifling.

III. Consequential ails, which may be enumerated as in the following articles.

1. The natural Effects of an intense corrosive scor­butick [Page 10]like colliquation of the Blood and Juices. Ana­sarcous swelling or blotedness of the face, in some to that degree as to shut up the Eyes; the same Oedemetous swellings in the extremities, in a few an Infiltration in the Scrotum, in some Petechiae, Purple spots, scorbutick like sugillations upon the leaft scratch or bruise; hamorrhages of all sorts, by the Nose, from the Lungs in expectoration, by Stool, by Urine, Profluniums in Women tempore non debito; these are dismal phanomina in the state of any acute Fever, u. g. Small Pox, and scarce any recover; but in our distemper being only short tem­porary consequential ails, scarce any of them prov­ed mortal, but gave way to a soft milk diet, in some to Cortex Peruw. or Elixir Vitrioli in others; a Girle aet. 14. with haemorrhages of several sorts, with Purple spots, and scorbutick like sugillations, recovered, notwithstanding of a very loose Regi­men. N. B. These were not to be attributed to the Mercurial administrations, because they equally happened to those who had taken no Mercury.

2. Where the desecation has not been compleat, from want of natural strength, or from catching cold, or from undue evacuations: the reliquiae were thrown off by Ʋrtications, by Vesications in several parts of the Body, by serpiginous eruptions chiefly in the face, by purulent Pustules, by Boils, by swel­lings and impostumations in the groin, armpits and other parts of the Body. The most frequent con­sequential ail of this kind is, when from cold re­ceived, the glands and cellulary tegument called the panicula adiposa in the fore part of the neck becomes infiltrated and obstructed; if not soon re­solved by the continued fotus of warm woollens and hot animating applications; the induration in­creases [Page 11]and spreads every way, so as to suffocate some, in others they sphacelate and become Ulcers mortal or of difficult cure: thus a few have died with us in Boston, but many in the Country. By catching cold likeways the Tonsils have afterwards inflamed and come to suppuration: In a young Woman the Tonsils and Ʋvula being much ulcera­ted, did unite and coalesce into one mass and re­main so; this might have been prevented by fre­quent gargling.

While these indurations are only in the form of Kernels as they are vulgarly called, woollen mufflers, Empl. de Ranis cum Mercurio and the like, with gentle Catharticks, soon resolves them. Cataplasms in this case have done much mischief; because so soon as they are become cold, they act as a chilling damp upon the part, and destroy its vitality. When they arrive to the state of putrid flaccid Ulcerations, digestives and soft fomentations in­tenerate tenerate the part and occasion the Ulcer to spread; spirituous animating desiccative dressings have done better. Exposing the part to the cold, either in state of Tumefaction only, or in the subsequent ex­ulcerations aggravates the ail.

3. From the violence which the Nerves have suffered in this Illness; even where the Symptoms were ap­parently mild, they all complain of great faintness and Universal weakness, particularly in the joints-Some Women have Hyfterick affections, in a few upon recovery imbecility of mind or silliness, in some stammering or loss of Speech for a few days, some have had short fits of Melancholy, some were seized with Epileptick fits, but not so as to become habitual. All these disorders soon vanished, as the Patient recovered his Strength in course of time, [Page 12]and by the help of a restorative cordial Regimen and diet.

4. Other consequential ails in common with other fevers; particularly where the Strength of nature has been much impared by the distemper it self, or by immoderate evacuations, the Patient is left in a languishing weakness. Where the Eruption has been impeded by being exposed to the cold, or by unseasonable Ʋ S. or Catharticks; the patient falls into Hectical wastings, fatal to some in a very short time. All who underwent immoderate evacuati­ons, were a long time in recovering of their Strength.

SCHOLIA or some general remarks upon the whole.

1. This seems to be a new kind of Epidemical dis­case. It is not the same with the Aphthae which have at times prevailed in Holland, as described by Forestus, and mentioned by Boerhaave in his Colleg­es. Tournefort says there is a distemper not uncom­mon in the Levant, viz a Carbuncle or plague sore in the bottom of the Throat; it carries off chil­dren in a few days, but does not affect grown People as does ours. Capt. Morton of late Ply­mouth Colony, who wrote many years ago his New. England Memorial, says that an. 1650. a disease in the Mouth and Throat prevailed, which proved mortal to many in a short time; but he does not describe it, and mentions nothing of a Fever. In Boston November 1719. a slight milary fever chiefly with children, but was over in two or three days, unless by catching cold it continued appearing and disappearing alternately for some days longer; there was no complaint of the Throat, and no deaths ensued. It is not the same with the sore Throats which are observed from [Page 13]time to time in some of our Country Towns, espe­cially in the Winter season: these are Endemial and constitutional, being tumefactious and exulce­ratious with fluxion in the Fauces and Neck; pro­ceeding from an intense scropholous, scorbutick, or Psorick habit (in such subjects vesications by Can­tharides did putrifie) without any Eruptive fever: ours have generally an Eruptive fever or tendency that way, so that of those who have died in Boston, not above one in seven died of any Throat ail, but of this fever. It is however observable that the Serophulous and Psorick, are most susceptible of this distemper, and suffer more remarkably.

2. This Epidemical distemper is no creature of the Seasons, it having prevailed from May 1735. when it first emerged, the whole year or all the Seasons round. It is no produce of peculiar climates and soils, because it hath made its appearance in various places from Pemaquid in 44 N. Lat. to Carolina South­ward, and as we are lately informed, it is in our West India Islands. It is remarkable that in damp places, as near large Ponds, fresh water Rivers, woodlands, and the like, it has done the greatest execution, as does the Rot amongst Sheep in fenny Lands.

It is not personally infecting after the rate of the Plague, Small Pox, &c. where every Person is sus­ceptible, excepting a very few anomolous constitu­tions. Children are the most obnoxious to any infection; but with us several Children in the family, where the distemper appeared, have escap­ed: it is true where it happens in a family, it fre­quently seizeth severals, as is the case with our Country Peripneumonick Fevers, and our Autumnal remitting slow Fevers, which cannot be said to be [Page 14]contagious. The distance in time of Infection to be supposed received from a sick Person, to the time of the distemper's appearing in the supposed infected, could never, with any reasonable allowance of latitude, be reduced to any rule, as in Small-Pox, Measles, &c. We have Anatomically inspected Persons who died of it with so intense a faetor from the violence of the disease, that some Practioners could not continue in the room; but without be­ing infected our selves or carrying it into families. Many children without reserve, frequent the hou­ses and chambers of the sick, and escape. It does therefore proceed from some undiscovered quality of the air, affecting only peculiar constitutions of persons and families: notwithstanding of its being generally favourable, it proves fatal to certain families; ma­ny families for this reason have buried all or most of their children, u. g. Boynton of Newbury-Falls lost his eight children, at Hampton-Falls in 5 fa­milies died 27 Persons.

3. This is a very anomalous Illness, some complain a day or two before they are confined, some are seized as it were instantaneously, it is generally most severe with these last. In some a soreness of the Throat and darting pain there, reaching the Ears, is previous to all other Symptoms; in others the common Symptoms of a fever appear, before any inflamation or specks are perceivable in the Fauces. Some have a sore Throat without any perceivable cruption, only a gentle breathing continued Sweat, or an increased insensible perspiration with the peculiar smell of the morbid effluvia. Some (but very few) have the cuticular eruptions without any sloughs in the Throat; only the Tonsils, Ʋvula, and velum Palati, tumified and inflamed; and in a few, [Page 15] a purulent discharge from some parts deeper than the Fauces, that is lower than the sight can reach, these are not without danger. Many of those who died early of a Necrosis, had no tumefaction, infla­mation or specks in the Throat.

The time of Eruption is very uncertain; in a very few it preceeds the soreness of the Throat, in a few it goes pari passu with the affection of the Fauces; but generally it is (not much) later than the first complaints of the Throat, in a young Woman it was later by 14 days.

In ruddy complexions the efflorescence is very discernable; it is not so distinctly perceivable in Brunets, Indians, and Negroes; unless the miliary Eruption have a considerable Relievo as in some, they generally scale and peal notwithstanding. Sometimes it appears only in the cheeks, sometimes only a few clusters in the extremities. Sometimes the suffusion was scarce miliary and vanished insen­sibly by becoming gradually paler without scaling. Where the Miliary Eruptions were considerable, the extremities peel in scraps or strips like Exuviae; in one or two the nails of the fingers and toes did cast off. The period or continuance of Eruption is sometimes prolonged by weakness of nature, by undue evacuations, or by the Patients being expos­ed to the cold.

4. In some who were very slightly affected, their Illness was of a much shorter continuance, than is described in the Standard kind. Most of those who died of the Physician died by immoderate evacuations. As to the deaths, only a few were occasioned im­mediately by any distemperature of the Throat; they were generally the effect of the Fever, either by an immediate Necrosis at first seizure, or by the [Page 16]ordinary fatality of Fevers, or by consequential ails. In Boston at a medium of the last eight heal­thy years (1723. 1724. 1725. 1726. 1727. 1728. 1732. and 1733) in the Months of October, Novem­ber, December, January, February, March, April to 18th May, died pr. an. 268 Whites and Slaves; this year in the same space of time died 382, is 114 extra deaths, and may be resonably charged to this Illness, it being otherways a healthy time: of these 114. about 71 cases came to my knowledge, whereof in the first period died 35, in the second period 28, and of consequential ails, 8. Of these 71, only about 10 can be said to have died of sore Throats. Of these 71 only 9 were upwards of 14 aet. According to the nearest estimate I can make in round numbers, about 1 in 35 have died, that is about 4000 Persons in Boston have had this distem­per, which is about one 4th part of the Inhabitants.

5. The Summer 1735 was unusually wet and chilly with many Easterly winds, in the Summer & Autumn it prevail'd and was very mortal in several Country Towns. In Boston it began in Autumn, but did not prevail until Winter, which was not rigid with hard frosts as is usual, but with a very disagreeable chill in the air, especially in the Month of March last, in which Month was our greatest Mortality.

6. Most Malignant distempers affect to throw off their malignancy by some Emunctory. The despumation of this acrid inqination of the juices in our distemper, that is, its natural Crisis, seems to be by the patent and salutary Emunctories of the Fauces and skin. In corrosive taints, u. g. Venereal and others, a Mer­curial ptyalism and sudorifick decoction of the woods, answer best; this gave us the hint of promoting [Page 17]the tendency of nature in our Illness, by Mercurials, and gentle breathing Sweats a bed; which with good management seldom fail'd, excepting where the Necrosis was irremediable from the beginning.

Some affiction of the Throat seems to attend most kinds of Eruptive Fevers. In the Small-Pox (even where the pustules and other Symptoms were in the smal­lest degree) they all complain of a soreness of the Throat, but without ulcerating. In the Measles there is a hoarsness, and soreness of the Throat. In ours besides the soreness, tumefaction, and inflam­mation in the Fauces; there are specks or sloughs of a mellow white or Cream colour, like those on the inside of the cheeks in a Mercurial ptyalism; the Scrophulous and Venereal ulcers in the Throat are yellow; Aphthae are more of the nature of phlyc­tenae; many of our Patients complain of a copperish taste or peppery smart in the Throat, as they ex­press it.

7. As in all other distempers so in this there do some­times happen violent Symptoms, meerly from the Regimen and Medicines used; which on that account are not of that bad consequence, as if they had proceeded from the distemper in its natural course u. g. in some constitutions a Turbith bolus operates with violence, so as to occasion shiverings, torsions of the Bowels, and Spaims, as if the Patient were moribund: Calomel even in very small doses seizeth the Mouth of some to a very considerable degree of inconveniency.

8 We did not observe any genuine second seizures. It is true, being Winter Season, many common sore Throats, that is, relaxations of the Ʋvula and in­flammations of the Tonsils; have passed with the less observing practitioners, for the genuine Epe­demick [Page 18]and were used accordingly; such have after­wards had this Illness, and was erroneously called a second seizure. N. B. Our Epidemick is attended with no cough, unless when complicated with a cold or some old habitual Tussis: upon recovery, it leaves frequently a small catarrhous colliquation or cough, but of short continuance.

In some after being well, upon catching cold, the Tonsils have been inflamed even to suppuration; in others the Ʋvula and Velum Palati infiltrated and some phlyctenae or common Aphthae, have appeared. Such have also by some been deem'd as second seizures, and used as such.

After a long continuance of cold chilly Weather, there set in suddenly warm Weather hot as mid Sum­mer. May 25th, 26th, &c. several children, who formerly had this Eruptive sever, have an efflorescence or miliary eruption by the heat, as is not unusual with children in hot weather: this was by mistake of some practitioners and others, called a second sei­zure.

9. No conditions of Mankind were exempted (in our Epidemical Autumnal dysentery A. 1734. the Ne­groes escaped) Europeans, West-India Islanders, Indi­ans and Negroes, of all ages, were equally subject to it: but, as in most Epidemical diseases, it affected Chil­dren and the younger Persons more generally.

10. This is a Real History of the distemper as it ap­peared in Boston New-England, taken clinically from the life and not copied. There is no stroak or clause, but what I can vouch by real not imaginary cases. It is founded only upon observations or phaenomina, that is upon the Symptoms that appeared in the course of this Epidemical disease; it must therefore be of permanent truth.

FINIS

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